Donation of medications is not possible for most drugs nor is it available to many people, so you will most likely be looking for a way to dispose of expired and unused medications. Although there are pros and cons for each, take-back programs are the preferred method of disposal. Unfortunately, finding a place to take back medications when you urgently need to do it is limited by an inadequate number of locations and restricted hours of operation. However, there are safe ways to dispose of them at home.
Take-back programs can be used to safely dispose of most types of unneeded medicines, including a few potentially dangerous ones. Potentially dangerous medications usually have instructions to dispose of them as soon as they are no longer needed. If a collection center or take-back event is not immediately available, specific directions may call for flushing them down the toilet or sink.
There are generally two kinds of take-back options: periodic events and permanent collection sites.
The U.S. Drug Enforcement Administration (DEA) hosts National Prescription Drug Take-Back events, usually twice a year, where temporary collection sites are set up in communities all over the country for safe disposal of prescription drugs.
All take-back sites must be DEA-registered collectors. The location of authorized permanent collection sites vary by community, but may be found in:
Some of these sites may also offer mail-back programs or collection receptacles, sometimes called “drop-boxes,” so you can dispose of them yourself.
The DEA Office of Diversion Control Registration Call Center may be called at 1-800-882-9539 to find an authorized collector in your community.
When no take-back programs, DEA-registered collectors, or take-back events are available in your area when you need them, it may become necessary to dispose of medications at home. There are two choices: throwing them in the trash or flushing them down the sink or toilet. Which of these you choose depends entirely on the medication.
When there is no take-back option, you will usually find specific disposal instructions for home disposal of a medicine.
If this information is not available there are two good sites to look at.
Most medicines can be thrown out in the trash and flushing is reserved for few hazardous medications and only if no take-back option is available.. The ‘flush list’ is presented in the table below.
In addition to checking the specific directions for disposal, take time to learn the local regulations and laws for your area.
If you can’t take your medications anywhere, you may dispose of most of them in the household trash.
Unless trying to dispose of an inhaler or sealed glass container, you can usually follow these steps.
For a number of reasons, inhalers cannot be disposed of in a medical waste disposal box, pharmaceutical disposal box, or sharps container.
When your containers are empty, delete all personal information on the prescription label of empty pill bottles or medicine packaging before you dispose of them.
Flushing is reserved for dangerous medications, usually opioids, that may be very harmful and, in some cases, fatal if used by someone other than the person for whom they were prescribed. Some may be especially harmful or more deadly to children and pets if taken accidentally.
Some medications are too dangerous to keep around the house or even dispose of in the trash, and should be disposed of immediately after they are no longer needed or have expired. The preferred method is still a take-back option, but flushing is Plan B if centers are not available for immediate disposal.
The Environmental Protection Agency opposes flushing. This is out of sync with the FDA, but it’s understandable why. The EPA focuses solely on the environmental impact of flushing, while the FDA also has to consider the safety issues associated with keeping dangerous medications around your house.
A small number of medicines have specific instructions to flush them down the toilet as soon as they are no longer needed, and only if an immediate take-back location or program is not an option.
Links from the brand names in the list below direct you to consumer information about medications which includes specific disposal instructions.
Links from the generic names go to detailed information about each medication.
|Generic Name||Brand Names|
|Buprenorphine||Belbuca, Bunavail, Butrans, Suboxone, Subutex, Zubsolv|
|Fentanyl||Abstral, Actiq, Duragesic, Fentora, Onsolis|
|Diazepam||Diastat/Diastat AcuDial rectal gel|
|Hydrocodone||Anexsia, Hysingla ER, Lortab, Norco, Reprexain, Vicodin, Vicoprofen, Zohydro ER|
|Methylphenidate||Ritalin, Methylin, Concerta, Daytrana transdermal patch system|
|Morphine||Arymo ER, Avinza, Embeda, Kadian, Morphabond ER, MS Contin|
|Oxycodone||Combunox, Oxaydo, OxyContin, Percocet, Percodan, Roxicet, Roxicodone, Roxybond, Targiniq ER, Xartemis XR, Xtampza ER|
Many, including the US Food & Drug Administration (FDA) and Environmental Protection Agency, worry about the environmental impact of flushing these medications into septic and sewage systems. However, as you will see, the impact of these medications alone is negligible.
The FDA recognizes their recommendation to flush potentially dangerous medicines raises questions about the impact on the environment and contamination of surface and drinking water supplies. Because of this, studies have looked at this impact and found it to be minimal.
The effort to address this concern resulted in the FDA publishing the paper “Risks Associated with the Environmental Release of Pharmaceuticals on the U.S. Food and Drug Administration ‘Flush List’.”
FDA has concluded that when a take-back option is not readily available, the risk of harm, including death, to humans from accidental exposure to certain medicines, especially potent opioids, far outweighs any potential risk to us or the environment from flushing them.
The FDA will continue to conduct these risk assessments as a part of larger activities related to the safe use of medicines.